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KMID : 0387720150260010001
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Korean Journal of Blood Transfusion
2015 Volume.26 No. 1 p.1 ~ p.8
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Transfusion Strategy and Laboratory Update on the DEL Variant
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서민희:Seo Min-Hee
김보람:Kim Bo-Rahm/권정란:Kwon Jeong-Ran/최영실:Choi Young-Sill/김준년:Kim Jun-Nyun/박경운:Park Kyoung-Un/조덕:Cho Duck
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Abstract
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Red cells that express extremely low levels of D antigen that cannot be detected by routine serologic tests are designated as DEL. Most DEL blood donors are typed as D-negative. However, DEL red blood cells can be recognized by serological adsorption and elution test or molecular RHD genotyping. Anti-D production in patients with D-negative who received transfusion containing DEL blood has reported, therefore distinction between DEL variant and true D- negative is clinically important. This review highlights a transfusion strategy and laboratory update on the DEL variant in the Korean population.
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KEYWORD
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RHD, DEL, Transfusion, Genotyping
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